What is mescaline?

Mescaline, also known as 3,4,5-trimethoxyphenethylamine, is a hallucinogenic drug that occurs naturally in certain cacti plants native to the southwest United States, Mexico, and South America. These plants include the peyote cactus (Lophophora williamsii), the San Pedro cactus (Trichocereus pachanoi), and the Peruvian Torch cactus (Trichocereus peruvianus).
Mescaline has been used by Native Americans for thousands of years in religious ceremonies and for the treatment of various physical ailments. Although the use of mescaline products is illegal in the United States, peyote is recognized as a sacrament in the Native American Church of North America.

Effects of mescaline

The effects of mescaline last for 10 to 12 hours, although the use of mescaline as a sacrament takes place over two days.1 As a hallucinogenic or psychedelic drug, mescaline induces an altered state of consciousness where people experience altered thinking and perception. People often describe this state as enjoyable, euphoric, and dream-like.

Visual hallucinations are a common effect of mescaline use, and people often describe distortions in their experience of time.

Health and Safety

Agitation—an emotional state of nervousness or nervous excitement—can occur out of nowhere when people take mescaline. It can also result from excessive worrying about other symptoms such as whether hallucinations are real or perceived heart problems. Agitation can quickly turn to panic for people who have taken hallucinogens, which can lead to dangerous agitated behavior such as running off into unsafe environments like city streets with traffic, or rural areas with environmental hazards such as heights, swamps, etc.

Hallucinations- People who use mescaline may see or hear things that are not there or have no actual basis in reality.2 Although hallucinations are an expected or even desired effect of hallucinogenic drugs, sometimes people find them much more troubling or frightening than expected. Although they typically know hallucinations that occur in a mescaline intoxicated state are not real, they can cause a lot of confusion and distress.

Tachycardia-O r rapid heart rate is defined as a heart rate of over 100 beats per minute (bpm).2 While there may not be severe physical consequences of tachycardia, a fast heart rate can sometimes create anxiety, which can further speed up heart rate. People can feel panicky, particularly if they are worried that using the drug is causing heart problems.